Researchers

Mike Bailey

Senior Principal Engineer

CIMU Department

APL-UW

Assistant Professor, Mechanical Engineering and Adjunct Assistant Professor, Urology

Justin Ahn

Resident

UW Urology

Wayne Brisbane

Resident

UW Urology

Matthew Bruce

Principal Scientist/Engineer

CIMU Department

APL-UW

Alana Clark

Research Coordinator

Institute of Translational Health Sciences

Larry Crum

Principal Physicist

CIMU Department

APL-UW

Research Professor, Electrical Engineering and Bioengineering

Bryan Cunitz

Engineer IV

CIMU Department

APL-UW

Barbrina Dunmire

Senior Engineer

CIMU Department

APL-UW

M. Kennedy Hall

Instructor

UW Emergency Medicine

Jonathan Harper

Assistant Professor

UW Department of Urology

Ryan Hsi

UW Department of Urology

Peter Kaczkowski

Principal Engineer

CIMU Department

APL-UW

Tatiana Khokhlova

Research Associate

CIMU

Vera Khokhlova

Senior Principal Engineer

CIMU Department

APL-UW

Wayne Kreider

Senior Engineer

CIMU Department

APL-UW

John Kucewicz

Senior Engineer

CIMU Department

APL-UW

Wei Lu

Research Assistant

CIMU Department

APL-UW

Brian MacConaghy

Physicist IV

CIMU Department

APL-UW

Philip C. May

Resident

UW Urology

Marla Paun

Senior Engineer

CIMU Department

APL-UW

Oleg Sapozhnikov

Senior Principal Engineer

CIMU Department

APL-UW

Julianna Simon

Research Associate

CIMU

Mathew Sorensen

Assistant Professor

UW Deptartment of Urology

Rusty Starr

Research Manager

CIMU Department

APL-UW

Jeff Thiel

Sonographer

UW Radiology

Yak-Nam Wang

Senior Engineer

CIMU Department

APL-UW

Funding

NIH

NSBRI

UW CoMotion

Washington Research Foundation

Institute of Translational Health Sciences

W. H. Coulter Foundation

Ultrasonic Detection, Propulsion + Comminution of Kidney Stones

Current Research at the University of Washington

Continuing R+D

Ultrasonic propulsion changes the game. It gives us the opportunity to reposition stones to relieve an obstruction and ease pain immediately.

Our ultimate goal is to develop a platform technology that will bring these different ideas together — imaging, targeting, fragmenting, and expelling stones — into one ultrasound unit that can be used for comprehensive kidney stone management.

Benefits for Urologists + Patients

Ultrasound has a lot of potential. You know these space-age things — using some wand to actually do something inside a patient’s body. That may actually come true. We can move stones.

Big efforts are detection and sizing, pushing stones, and also breaking stones. If it works like we hope it will, it could replace the majority of the stone treatments that we do.

An All-in-One Kidney Stone Treatment System

This research is developing a new ultrasound device to detect, size, fragment, and expel kidney stones.

Stone Detection + Sizing (S-Mode). Our B-Mode ultrasound imaging has been customized to enhance stone contrast with surrounding tissue. In addition, we have optimized the Doppler 'twinkling' to aid in the detection of kidney stones.

Stone Targeting + Repositioning. The same ultrasound probe that is used for imaging is used to reposition kidney stones and stone motion is monitored with B-mode in real time.

Burst Wave Lithotripsy (BWL). We are investigating a new mechanism for stone fragmentation. Burst waves of lower pressure than shockwaves can be used to break stones into barticles < 2 mm. Treatments could potentially be faster and with less injury than ESWL.

Continuing Research

  • Further optimization of push force profile
  • Safety and effectiveness testing of BWL
  • Automated stone detection algorithms
  • In vivo validation of stone detection and sizing

From Researchers' Ideas to Clinical Trials

Patient Trials Begin
Pathway to Clinic
Prototype Demo
R & D

This dedicated ultrasound system is capable of non-invasive, real-time, image-guided repositioning of kidney stones. We can move stones while patients are awake so there’s no pain — this can be an office procedure. The real goal is to relocate small stones to facilitate their passage.

This is completely novel technology. There’s nothing like it out there.

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