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Pierre Mourad
Dr. Mourad, Dr. Antao Chen, and Dr. Joel Berg (UW Dept. of Pediatric Dentistry) will build and test a bench-top LED (light-emitting diode) device to identify locations in teeth where cavities are likely to form. Light of a given wavelength illuminates tooth enamel to produce an autofluorescence signal. Teeth with normal and normal amounts of enamel autofluoresce significantly while pre-cavities created by plaque bacteria and actual cavities have a weak autofluorescence signal due to the alteration and/or absence of enamel. The device will be the first inexpensive and simple system to identify cavity formation without lasers.
Mike Bailey
Dr. Bailey will make improvements to and test a new system for determining when kidney stones have broken up completely during treatment. This feedback will lessen damage to the kidneys and surrounding tissue by reducing the number of shock waves used in treatment.
Daniel Leotta
Dr. Leotta will modify and test an ultrasound-based system to detect breast cancer and monitor the effectiveness of chemotherapy. The ultrasound system detects small, early stage tumors (an improvement over x-ray mammography) by detecting new blood vessels associated with malignant tumors.
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Larry Crum
The funds are being used to support the design, construction, and testing of a prototype device that uses high intensity ultrasound to ablate and cauterize tissues in laparoscopic surgical procedures. The device will reduce blood loss and preserve more of the organ of interest.
Dr. Crum and colleagues presented a two-part lecture "Bloodless Surgery" on the innovations in high intensity focused ultrasound research at the UW Mini-Medical School lecture series. Go to UWTV to watch the program.
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